Discover how caspase-8 regulates T-cell senescence and its potential to enhance adoptive cell therapy for cancer treatment.
Discover how immune-based classification of soft-tissue sarcoma is revolutionizing cancer treatment through tertiary lymphoid structures and personalized immunotherapy approaches.
Exploring breakthroughs in germ cell tumour research, including immune profiling and innovative iNKT cell therapy for complete remission.
Groundbreaking research on neoadjuvant immune checkpoint blockade for malignant pleural mesothelioma treatment, offering new hope for patients.
Discover how genetically engineered mice are helping scientists create better CAR-T cell therapies to fight cancer by studying natural CAR splicing variants.
Discover how PD-L2, the lesser-known immune checkpoint protein, plays a critical role in B-cell lymphoma and opens new avenues for cancer immunotherapy.
Discover how c-Abl protein modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity (ADCC) and enhances cancer immunotherapy effectiveness.
Discover how LAG-3, PD-1, and TIM-3 work together in breast cancer to suppress immune response and how combination therapies could overcome resistance.
Discover how single-cell analysis is transforming our understanding of liver cancer immunotherapy resistance and response.
Explore the genomic architecture of 4-1BB (CD137), its role in immune regulation, and its transformative potential in cancer immunotherapy.