Discover how genetically engineered mice are helping scientists create better CAR-T cell therapies to fight cancer by studying natural CAR splicing variants.
Discover how PD-L2, the lesser-known immune checkpoint protein, plays a critical role in B-cell lymphoma and opens new avenues for cancer immunotherapy.
Discover how c-Abl protein modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity (ADCC) and enhances cancer immunotherapy effectiveness.
Discover how LAG-3, PD-1, and TIM-3 work together in breast cancer to suppress immune response and how combination therapies could overcome resistance.
Discover how single-cell analysis is transforming our understanding of liver cancer immunotherapy resistance and response.
Explore the genomic architecture of 4-1BB (CD137), its role in immune regulation, and its transformative potential in cancer immunotherapy.